Yolanda BW.indd
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چکیده
Objective We sought to assess blood fl ow in relation to jugular lymphatic distension in fetuses with increased and normal nuchal translucency (NT). Study design In all, 72 fetuses with normal NT and 71 fetuses with NT > 95th percentile were evaluated. NTsize, jugular lymphatic sacs (JLS), jugular vein and ductus venosus pulsatility index for veins (PIV), and intracardiac velocities were measured. Results JLS were visualized in 22/72 fetuses with normal and in 55/71 fetuses with increased NT. Jugular vein and ductus venosus PIV was higher in fetuses with increased NT compared to normal NT (P < .01). Visibility of JLS was associated with a higher ductus venous PIV (P < .05), but not with a higher jugular vein PIV. Larger NT and larger JLS volumes were associated with higher jugular vein and ductus venosus PIV (P < .05). Conclusion This study shows a relation between increased NT, jugular lymphatic distension and altered blood fl ow in jugular vein and ductus venosus. Yolanda BW.indd 34 21-12-10 13:52
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Yolanda BW.indd
Objective Increased nuchal translucency in the human fetus is associated with aneuploidy, structural malformations and several syndromes such as Noonan syndrome. In 60-70% of the Noonan syndrome cases, a gene mutation can be demonstrated. Previous research showed that aneuploid fetuses with increased nuchal translucency demonstrate an aberrant lymphatic endothelial diff erentiation. Methods Fet...
متن کاملYolanda BW.indd
Objective To assess the ultrasonographic appearance of the jugular lymphatic sacs (JLS) in fi rst-trimester fetuses with a normal nuchal translucency (NT). Methods Seventy-fi ve fetuses with a normal NT thickness (< 95th percentile) were examined weekly between 11 and 17 weeks of gestation. After measurement of the NT thickness, the neck region was examined using both transvaginal and transabdo...
متن کاملYolanda BW.indd
Objective The purpose of this study was to evaluate ductus venosus fl ow velocities and a possible relationship with the type of cardiac defect in fetuses with increased nuchal translucency (NT). Methods Seventy-two fetuses with normal NT and 137 fetuses with increased NT (>95th percentile) were evaluated. The ductus venosus pulsatility index for veins (PIV), late diastolic velocity (velocity d...
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